Chronic Liver Disease (CLD) | Alcoholic Liver Disease (ALD)

Alcoholic LIver Disease< (ALD)
 
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Alcoholic Liver Disease (ALD)
Alcoholic Liver Disease (ALD) is relatively more common in seniors. Alcoholic liver disease often presents initially in the elderly, with one study reporting that 28% of patients first presented after age 60. In one study, the 1-year mortality rate for cirrhotic patients over age 60 was 50% versus 7% for patients under age 60. Importantly, this study, which biopsied 96% of its subjects, identified that 100% (n = 7) of men aged over 70 years presenting with ALD had cirrhosis on biopsy, compared to 55% (n = 112) in men aged 20-59 years (6).
ALD world-wide: Alcoholic Steatohepatitis (ASH) is the number one cause of liver fibrosis/cirrhosis as related to liver transplantations (7). ASH population prevalence percentage rate correlates with the age of the population, the popularity or prevalence of drinking, the types of alcoholic drinks consumed (see above).
ALD US: Alcoholic Steatohepatitis (ASH) is the number cause of liver fibrosis/cirrhosis as related to liver transplantations (7). ASH population prevalence percentage rate correlates with the age of the population, the popularity or prevalence of drinking, and the types of alcoholic drinks consumed (see above). All of these parameters may be influenced by regional or cultural influences.
ALD AZ: Because Arizona's population has a disproportionately higher percentage of senior citizens, Arizona's ASH population prevalence percentage rates would be expected to be higher than the national average (see above).
ALD Maricopa County: Because Maricopa County's population has a disproportionately higher percentage of senior citizens, Maricopa County's ASH population prevalence percentage rates would also be expected to be higher than the national average (see above).


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CITATIONS:

(1) http://www.medscape.com/viewarticle/746578_5

Alimentary Pharmacology & Therapeutics Systematic Review The Epidemiology and Natural History of Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis in AdultsG. Vernon, A. Baranova, Z. M. Younossi

Aliment Pharmacol Ther. 2011;34(3):274-285.

(2)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229518/

World J Gastroenterol. Nov 14, 2014; 20(42): 15532–15538.

Published online Nov 14, 2014. doi: 10.3748/wjg.v20.i42.15532

Liver transplantation and non-alcoholic fatty liver disease

Petros Zezos and Eberhard L Renner

(3) Aliment Pharmacol Ther. 2011 Aug; 34(3):274-85. Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults. Vernon G, Baranova A, Younossi ZM

(4) Gastroenterology. 2011 Jan; 140(1):124-31. Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: a prospective study. Williams CD, Stengel J, Asike MI, Torres DM, Shaw J, Contreras M, Landt CL, Harrison SA

(5) J Clin Gastroenterol. 2006 Mar; 40 Suppl 1():S17-29. Pathophysiology of nonalcoholic steatohepatitis. McCullough AJ

(6) Gerontology 1987;33:380-7.Clinical features and prognosis of alcoholic liver disease in respect of advancing age. Potter J, James O.

(7) Liver Transplantation Volume 10, Issue 8, August 2004 Older age and liver transplantation: A review Rajesh N. Keswani, Aijaz Ahmed, Emmet B. Keeffe *Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA

(8) http://www.hepatitisc.uw.edu/pdf/screening-diagnosis/epidemiology-us/core-concept/all

HCV Epidemiology in the United States - Hepatitis C online

(9) http://wwwnc.cdc.gov/travel/yellowbook/2014/chapter-3-infectious-diseases-related-to-travel/hepatitis-c

Center for Disease Control and Prevention – online

(10) http://www.liverfoundation.org/downloads/alf_download_199.pdf

The Liver Foundation - online

(12) Hepatology. 2010 Feb;51(2):454-62. Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease. Wong VW1, Vergniol J, Wong GL, Foucher J, Chan HL, Le Bail B, Choi PC, Kowo M, Chan AW, Merrouche W, Sung JJ, de Lédinghen V.

The LiverLab, located in Scottsdale, Arizona, is currently the only independant Liver FibroScan lab facility in the Metro Phoenix region. In addition to Scottsdale and Phoenix, AZ, the LiverLab services patients from the entire Phoenix Metro area to include Tempe, AZ; Mesa, AZ; Gilbert and Chandler, AZ and Glendale, Peoria, Surprise and Sun City, Arizona as well as other cities.


 
 

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